Publications

Simvastatin inhibits Wnt/β-catenin pathway in uterine leiomyoma.

El Sabeh M, Saha SK, Afrin S, and Borahay MA. Endocrinology 2021 Oct 6; doi: 10.1210/endocr/bqab211. Online ahead of print.

Simvastatin Modulates Estrogen Signaling in Uterine Leiomyoma via Regulating Receptor Palmitoylation, Trafficking and Degradation.

Afrin S, El Sabeh M, Islam MS, Miyashita-Ishiwata M, Malik M, Catherino WH, Akimzhanov AM, Boehning D, Yang Q, Al-Hendy A, Segars JH, Borahay MA.

Pharmacol Res. 2021 Aug 27:105856. doi: 10.1016/j.phrs.2021.105856. Online ahead of print.PMID: 34461224

Fast Forward: Fibroid Management in 2042.

El Sabeh M, Borahay M.

F&S Sci. 2021 May;2(2):114-115. doi: 10.1016/j.xfss.2021.02.002. Epub 2021 Feb 17. PMID: 34355207

Extracellular matrix and Hippo signaling as therapeutic targets of antifibrotic compounds for uterine fibroids.

Islam MS, Afrin S, Singh B, Jayes FL, Brennan JT, Borahay MA, Leppert PC, Segars JH.

Clin Transl Med. 2021 Jul;11(7):e475. doi: 10.1002/ctm2.475.PMID: 34323413

Diet and Nutrition in Gynecological Disorders: A Focus on Clinical Studies.

Afrin S, AlAshqar A, El Sabeh M, Miyashita-Ishiwata M, Reschke L, Brennan JT, Fader A, Borahay MA.

Nutrients. 2021 May 21;13(6):1747. doi: 10.3390/nu13061747.PMID: 34063835

Vascular Biology of Uterine Fibroids: Connecting Fibroids and Vascular Disorders.

Kirschen GW, AlAshqar A, Miyashita-Ishiwata M, Reschke L, El Sabeh M, Borahay MA.

Reproduction. 2021 May 1:REP-21-0087.R2. doi: 10.1530/REP-21-0087. Online ahead of print.PMID: 34034234

The Future of Uterine Fibroid Management: a More Preventive and Personalized Paradigm.

El Sabeh M, Borahay MA.

Reprod Sci. 2021 May 18. doi: 10.1007/s43032-021-00618-y. Online ahead of print.PMID: 34008153

Wnt/β-catenin signaling pathway in uterine leiomyoma: role in tumor biology and targeting opportunities.

El Sabeh M, Saha SK, Afrin S, Islam MS, Borahay MA.

Mol Cell Biochem. 2021 May 17. doi: 10.1007/s11010-021-04174-6. Online ahead of print.PMID: 33999334

Role of Inflammation in Benign Gynecologic Disorders: From Pathogenesis to Novel Therapies.

AlAshqar A, Reschke L, Kirschen GW, Borahay MA.

Biol Reprod. 2021 Mar 19:ioab054. doi: 10.1093/biolre/ioab054. Online ahead of print.PMID: 33739368

Uterine Stem Cells and Benign Gynecological Disorders: Role in Pathobiology and Therapeutic Implications.

El Sabeh M, Afrin S, Singh B, Miyashita-Ishiwata M, Borahay M.

Stem Cell Rev Rep. 2020 Nov 5. doi: 10.1007/s12015-020-10075-w. Online ahead of print. PMID: 33155150

Safety and efficacy of robotic-assisted Burch for pure stress urinary incontinence: a large case series.

Lee TG, Unlu BS, Petruzzi VA, Borahay MA, Dursun F, Saad AF, Kilic GS.

J Obstet Gynaecol. 2020 Oct 16:1-4. doi: 10.1080/01443615.2020.1803239. Online ahead of print.PMID: 33063572

Predictors of the Cost of Hysterectomy for Benign Indications.

AlAshqar A, Goktepe ME, Kilic GS, Borahay MA.

J Gynecol Obstet Hum Reprod. 2020 Oct 8:101936. doi: 10.1016/j.jogoh.2020.101936. PMID: 33039600

Association of preoperative sleep pattern with post-hysterectomy pain: a pilot study.

Nowakowski S, Levy-Meeks ME, Dawson DB, Meers JM, Stout-Aguilar JS, Kilic GS, Borahay MA.

J Clin Sleep Med. 2020 Aug 10. doi: 10.5664/jcsm.8730. Online ahead of print.PMID: 32776870

Liposomal 2-Methoxyestradiol Nanoparticles for Treatment of Uterine Leiomyoma in a Patient-Derived Xenograft Mouse Model.

Borahay MA, Vincent KL, Motamedi M, Tekedereli I, Salama SA, Ozpolat B, Kilic GS.

Reprod Sci. 2020 Jul 6. doi: 10.1007/s43032-020-00248-w. Online ahead of print. PMID: 32632769

Patient-Centered, Gynecology-Specific Prioritization of Non-urgent Surgeries During the COVID-19 Pandemic: Proposal of a Novel Scoring System.

Borahay MA, Wethington SL, Wang KC, Christianson MS, Martin S, Lawson SM, Esguerra C, Lippitt MH, Wu H, Handa VL, Satin AJ, Fader AN.

J Minim Invasive Gynecol. 2020 Jun 3;S1553-4650(20)30259-4. doi: 10.1016/j.jmig.2020.05.026. PMID: 32504823

Simvastatin ameliorates altered mechanotransduction in uterine leiomyoma cells.

Afrin S, Islam MS, Patzkowsky K, Malik M, Catherino WH, Segars JH, Borahay MA.

Am J Obstet Gynecol. 2020 May 14:S0002-9378(20)30537-8. doi: 10.1016/j.ajog.2020.05.012. PMID: 32417359

Impact of timing on wound dressing removal after caesarean delivery: a multicentre, randomised controlled trial.

Kilic GS, Demirdag E, Findik MF, Lutfi Tapisiz O, Sak ME, Altinboga O, Sak S, Unlu BS, Evsen MS, Zeybek B, Borahay M, Kuo YF.

J Obstet Gynaecol. 2020 Apr 21:1-5. PMID: 32312139

Association of demographic, clinical, and hospital-related factors with use of robotic hysterectomy for benign indications: A national database study.

Smith AJB, AlAshqar A, Chaves KF, Borahay MA.

Int J Med Robot 2020 Apr 10:e2107. PMID: 32276286

Cardiometabolic Risk Factors and Benign Gynecologic Disorders

AlAshqar A, Patzkowsky K, Afrin S, Wild r, Taylor HS Borahay MA.

Obstet Gynecol Surv 2019 Nov. 74 (11), 661-673. PMID 31755543

Weaning From Long-term Opioid Therapy.

Moss C, Bossano C, Patel S, Powell A, Chan Seay R, Borahay MA.

Clin Obstet Gynecol. 2019 Mar;62(1):98-109. doi: 10.1097/GRF.0000000000000425. Review.

Simvastatin, at clinically relevant concentrations, affects human uterine leiomyoma growth and extracellular matrix production.

Malik M, Britten J, Borahay M, Segars J, Catherino WH.

Fertil Steril. 2018 Dec;110(7):1398-1407.e1. doi: 10.1016/j.fertnstert.2018.07.024.

Pelvic Pain and Apical Prolapse Surgery: A Population-Based Retrospective Cohort Study.

Borahay MA, Zeybek B, Patel P, Lin YL, Kuo YF, Kilic GS.

Female Pelvic Med Reconstr Surg. 2018 Nov 27. doi: 10.1097/SPV.0000000000000674. [Epub ahead of print]

Outcomes of robotic, laparoscopic, and open hysterectomy for benign conditions in obese patients

Borahay MA, Tapısız ÖL, Alanbay İ, Kılıç GS.

J Turk Ger Gynecol Assoc. 2018 Jun 4;19(2):72-77. doi: 10.4274/jtgga.2018.0018. Epub 2018 Apr 27.

Therapeutic Roles of Statins in Gynecology and Obstetrics: The Current Evidence.

Zeybek B, Costantine M, Kilic GS, Borahay MA.

Reprod Sci. 2018 Jun;25(6):802-817. doi: 10.1177/1933719117750751. Epub 2018 Jan 10. Review.

New and Emerging Therapies for Uterine Fibroids.

Fritton K, Borahay MA.

Semin Reprod Med. 2017 Nov;35(6):549-559. doi: 10.1055/s-0037-1606303. Epub 2017 Nov 3. Review. No abstract available.

Medicolegal Review: Essure Lawsuits and Legal Strategies Adverse to Gynecologists.

Klimczak AM, Snyder RR, Borahay MA, Phelps JY.

J Minim Invasive Gynecol. 2017 Jul - Aug;24(5):727-730. doi: 10.1016/j.jmig.2017.02.017. Epub 2017 Feb 27. Review.

Robot-Assisted Abdominal Cerclage During Pregnancy.

Zeybek B, Hill A, Menderes G, Borahay MA, Azodi M, Kilic GS.

JSLS. 2016 Oct-Dec;20(4). pii: e2016.00072.

Estrogen Receptors and Signaling in Fibroids: Role in Pathobiology and Therapeutic Implications.

Borahay MA, Asoglu MR, Mas A, Adam S, Kilic GS, Al-Hendy A.

Reprod Sci. 2017 Sep;24(9):1235-1244. doi: 10.1177/1933719116678686. Epub 2016 Nov 20. Review.

Corrigendum to "Incidence of occult leiomyosarcoma in presumed morcellation cases: a database study" [Eur J Obstet Gynecol Reprod Biol 197 (2016) 31-5].

Rodriguez AM, Zeybek B, Asoglu MR, Sak ME, Tan A, Borahay MA, Kilic GS.

Eur J Obstet Gynecol Reprod Biol. 2016 Dec;207:247. doi: 10.1016/j.ejogrb.2016.10.007. Epub 2016 Oct 22. No abstract available.

Management of the Jehovah's Witness in Obstetrics and Gynecology: A Comprehensive Medical, Ethical, and Legal Approach.

Zeybek B, Childress AM, Kilic GS, Phelps JY, Pacheco LD, Carter MA, Borahay MA.

Obstet Gynecol Surv. 2016 Aug;71(8):488-500. doi: 10.1097/OGX.0000000000000343. Review.

The impact of a simulation-based training lab on outcomes of hysterectomy.

Asoğlu MR, Achjian T, Akbilgiç O, Borahay MA, Kılıç GS.

J Turk Ger Gynecol Assoc. 2016 Jan 12;17(2):60-4. doi: 10.5152/jtgga.2016.16053. eCollection 2016.

Statin use and uterine fibroid risk in hyperlipidemia patients: a nested case-control study.

Borahay MA, Fang X, Baillargeon JG, Kilic GS, Boehning DF, Kuo YF.

Am J Obstet Gynecol. 2016 Dec;215(6):750.e1-750.e8. doi: 10.1016/j.ajog.2016.06.036. Epub 2016 Jun 28.

Overcoming the obstacles of visualization in robotically assisted abdominal cerclage using indocyanine green.

Zeybek B, Borahay M, Kilic GS.

J Robot Surg. 2016 Dec;10(4):361-364. Epub 2016 Apr 19.

The role of 15-lipoxygenase-1 expression and its potential role in the pathogenesis of endometrial hyperplasia and endometrial adenocarcinomas.

Sak ME, Alanbay I, Rodriguez A, Gokaslan T, Borahay M, Shureiqi I, Kilic GS.

Eur J Gynaecol Oncol. 2016;37(1):36-40.

Incidence of occult leiomyosarcoma in presumed morcellation cases: a database study.

Rodriguez AM, Zeybek B, Asoglu MR, Sak ME, Tan A, Borahay MA, Kilic GS.

Eur J Obstet Gynecol Reprod Biol. 2016 Feb;197:31-5. doi: 10.1016/j.ejogrb.2015.11.009. Epub 2015 Nov 28. Erratum in: Eur J Obstet Gynecol Reprod Biol. 2016 Dec;207:247. Zeybek B [added].

Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy.

Borahay MA, Al-Hendy A, Kilic GS, Boehning D.

Mol Med. 2015 Apr 13;21:242-56. doi: 10.2119/molmed.2014.00053. Review.

Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study.

Borahay MA, Vincent K, Motamedi M, Sbrana E, Kilic GS, Al-Hendy A, Boehning D.

Am J Obstet Gynecol. 2015 Aug;213(2):196.e1-8. doi: 10.1016/j.ajog.2015.03.055. Epub 2015 Mar 31.

Impact of current video game playing on robotic simulation skills among medical students.

Öge T, Borahay MA, Achjian T, Kılıç SG.

J Turk Ger Gynecol Assoc. 2015 Mar 1;16(1):1-4. doi: 10.5152/jtgga.2015.15188. eCollection 2015.

Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells.

Borahay MA, Kilic GS, Yallampalli C, Snyder RR, Hankins GD, Al-Hendy A, Boehning D.

J Biol Chem. 2014 Dec 19;289(51):35075-86. doi: 10.1074/jbc.M114.583575. Epub 2014 Oct 30.

Assessment of minimally invasive surgical skills of pre-medical students: What can we learn from future learners?

Borahay MA, Jackson M, Tapısız OL, Lyons E, Patel PR, Nassar R, Kılıç GS.

J Turk Ger Gynecol Assoc. 2014 Jun 1;15(2):69-73. doi: 10.5152/jtgga.2014.0044. eCollection 2014.

A financial analysis of operating room charges for robot-assisted gynaecologic surgery: Efficiency strategies in the operating room for reducing the costs.

Zeybek B, Oge T, Kılıç CH, Borahay MA, Kılıç GS.

J Turk Ger Gynecol Assoc. 2014 Mar 1;15(1):25-9. doi: 10.5152/jtgga.jtgga.2014.79989. eCollection 2014.

Trends in the national distribution of laparoscopic hysterectomies from 2003 to 2010.

Lee J, Jennings K, Borahay MA, Rodriguez AM, Kilic GS, Snyder RR, Patel PR.

J Minim Invasive Gynecol. 2014 Jul-Aug;21(4):656-61. doi: 10.1016/j.jmig.2014.01.012. Epub 2014 Jan 24.

Outpatient robotic hysterectomy: clinical outcomes and financial analysis of initial experience.

Borahay MA, Patel PR, Kilic CH, Kilic GS.

Int J Med Robot. 2014 Jun;10(2):244-50. doi: 10.1002/rcs.1565. Epub 2014 Jan 6.

Outcomes of robotic sacrocolpopexy using barbed delayed absorbable sutures.

Borahay MA, Oge T, Walsh TM, Patel PR, Rodriguez AM, Kilic GS.

J Minim Invasive Gynecol. 2014 May-Jun;21(3):412-6. doi: 10.1016/j.jmig.2013.11.002. Epub 2013 Nov 18.

Initial experience with robotic retropubic urethropexy compared to open retropubic urethropexy.

Patel PR, Borahay MA, Puentes AR, Rodriguez AM, Delaisse J, Kilic GS.

Obstet Gynecol Int. 2013;2013:315680. doi: 10.1155/2013/315680. Epub 2013 Sep 8.

Disparities in use of laparoscopic hysterectomies: a nationwide analysis.

Patel PR, Lee J, Rodriguez AM, Borahay MA, Snyder RR, Hankins GD, Kilic GS.

J Minim Invasive Gynecol. 2014 Mar-Apr;21(2):223-7. doi: 10.1016/j.jmig.2013.08.709. Epub 2013 Sep 4.

Intraocular pressure and steep Trendelenburg during minimally invasive gynecologic surgery: is there a risk?

Borahay MA, Patel PR, Walsh TM, Tarnal V, Koutrouvelis A, Vizzeri G, Jennings K, Jerig S, Kilic GS.

J Minim Invasive Gynecol. 2013 Nov-Dec;20(6):819-24. doi: 10.1016/j.jmig.2013.05.005. Epub 2013 Aug 12.

Reply:.

Borahay MA, Kilic GS.

J Minim Invasive Gynecol. 2013 Sep-Oct;20(5):730-1. doi: 10.1016/j.jmig.2013.07.012. Epub 2013 Aug 3. No abstract available.

Mullerian inhibiting substance suppresses proliferation and induces apoptosis and autophagy in endometriosis cells in vitro.

Borahay MA, Lu F, Ozpolat B, Tekedereli I, Gurates B, Karipcin S, Kilic GS.

ISRN Obstet Gynecol. 2013 Jun 19;2013:361489. doi: 10.1155/2013/361489. Print 2013.

Modular comparison of laparoscopic and robotic simulation platforms in residency training: a randomized trial.

Borahay MA, Haver MC, Eastham B, Patel PR, Kilic GS.

J Minim Invasive Gynecol. 2013 Nov-Dec;20(6):871-9. doi: 10.1016/j.jmig.2013.06.005. Epub 2013 Jun 28.

Cytology at the time of cervical colposcopy.

Tapisiz OL, Ertan K, Tyner J, Borahay M, Freeman DH, Kilic GS.

Eur J Gynaecol Oncol. 2013;34(1):36-8.

Robotic-assisted, ultrasound-guided abdominal cerclage during pregnancy: overcoming minimally invasive surgery limitations?

Walsh TM, Borahay MA, Fox KA, Kilic GS.

J Minim Invasive Gynecol. 2013 May-Jun;20(3):398-400. doi: 10.1016/j.jmig.2013.01.001. Epub 2013 Mar 15.

Intermedin/adrenomedullin 2 is associated with implantation and placentation via trophoblast invasion in human pregnancy.

Havemann D, Balakrishnan M, Borahay M, Theiler R, Jennings K, Endsley J, Phelps J, Hankins GD, Yallampalli C, Chauhan M.

J Clin Endocrinol Metab. 2013 Feb;98(2):695-703. doi: 10.1210/jc.2012-2172. Epub 2013 Jan 21.

PMID:

Effect of residents' previous laparoscopic surgery experience on initial robotic suturing experience.

Kilic GS, Walsh TM, Borahay M, Zeybek B, Wen M, Breitkopf D.

ISRN Obstet Gynecol. 2012;2012:569456. doi: 10.5402/2012/569456. Epub 2012 Sep 2.

Accuracy of physician and nurse practitioner colposcopy to effect improved surveillance of cervical cancer.

Kilic G, England J, Borahay M, Pedraza D, Freeman D, Snyder R, Ertan AK.

Eur J Gynaecol Oncol. 2012;33(2):183-6.

Increased Apoptosis in Chorionic Trophoblasts of Human Fetal Membranes with Labor at Term.

Harirah HM, Borahay MA, Zaman W, Ahmed MS, Hankins GD.

Int J Clin Med. 2012;3(2):136-142.

Comparison of Perioperative Outcomes of Total Laparoscopic and Robotically Assisted Hysterectomy for Benign Pathology during Introduction of a Robotic Program.

Kilic GS, Moore G, Elbatanony A, Radecki C, Phelps JY, Borahay MA.

Obstet Gynecol Int. 2011;2011:683703. doi: 10.1155/2011/683703. Epub 2011 Oct 5.

Disseminated Intravascular Coagulation, Hemoperitoneum, and Reversible Ischemic Neurological Deficit Complicating Anaphylaxis to Prophylactic Antibiotics during Cesarean Delivery: A Case Report and Review of Literature.

Borahay MA, Harirah HM, Olson G, Kilic GS, Karipcin S, Hankins GD.

AJP Rep. 2011 Sep;1(1):15-20. doi: 10.1055/s-0030-1271219. Epub 2011 Jan 24.

Potential liability of reproductive endocrinologists for high order multiple gestation.

Borahay M, Phelps J.

J Assist Reprod Genet. 2010 Apr;27(4):157-9. doi: 10.1007/s10815-010-9397-4. Epub 2010 Mar 2. Review.

Catechol-o-methyltransferase expression and 2-methoxyestradiol affect microtubule dynamics and modify steroid receptor signaling in leiomyoma cells.

Salama SA, Kamel MW, Botting S, Salih SM, Borahay MA, Hamed AA, Kilic GS, Saeed M, Williams MY, Diaz-Arrastia CR.

PLoS One. 2009 Oct 7;4(10):e7356. doi: 10.1371/journal.pone.0007356. Erratum in: PLoS One. 2013;8(1). doi:10.1371/annotation/8c8c0cae-7f2f-4f37-9807-2d02b6c14db1.

Systemic lupus erythematosus presenting with leukocytoclastic vasculitis and seizure during pregnancy.

Borahay MA, Kelly BC, Harirah HM.

Am J Perinatol. 2009 Jun;26(6):431-5. doi: 10.1055/s-0029-1214241. Epub 2009 Mar 26.